Cellinsight.online Everything about human ageing and related diseases Apoptosis and necrosis are they accelerate aging? apoptosis Apoptosis is programmed cell death. Apoptosis is a Greek word means "falling off".In a multicellular organism if cells are no longer needed,or it's DNA damaged and cannot be repaired,then the cells commits suicide by a process called programmed cell death or the Apoptosis. In human beings billions of cells die in bone marrow and intestine every hour .since 19th century scientists noticed and described about apoptosis but a clear definition was given by John Foxton Kerr at the university of Queensland in 1972.Later Hovitz,Sydney Brenner,and John E Samson identified the genes involved in apoptosis. In 2002 they got Nobel prize in medicine Apoptosis and necrosis In our body,cells are produced by cell multiplication (mitosis) and the apoptosis is used to the destruction of cells. Around 100,000 cells are produced in our body per second and
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Replication and new virion formation
Generally all viruses are intracellular parasites,it replicate only after infecting a host cell, corona virus have bigger genome when compared to other viruses such as HIV viruses,influenza viruses,Ebola virus,etc.The genome consist of four structural proteins and eight gens for small accessary proteins and a replicase gene,when corona virus enter in to the cell it's RNA look like messenger RNA(mRNA),which tells the cell what protein to make,as soon as RNA get into the cell protein making machinery begins to starts reading the viral genes,and making the proteins what they describes,after the cell made both proteins RNAs some of the RNA molecules get wrapped up with copies of the neucleocapsid proteins and then they are provided with envelop made of lipids,the assembling process takes place in the cellular work shop called Golgi apparatus,a cell may makes 100-1000 virions in this way,these virions enter other cells or body.
Precautions
If you touch contaminated surface wash your hands,don't touch your mouth eye or nose before washing hands,personal contacts is the most common reason for spreading the disease.
Vaccines
Vaccine development is underway,it will take at least 12-18 month to get any approved and effective vaccine for COVID-19,it is heard that now a days doctors are using hydroxychloroquinin(the old drug that used for malaria)along with Azithromycin.
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