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Showing posts from March, 2020

Role of protein on ageing

Role of protein on aging Protein which controls the length of telomere are telomerase and a protein complex known as shelterin.a new study by Scripps Reserch Institute (TSRI) discovered a new protein named as TZAP (telomeric zinc associated protein)which decrease the length of telomeres by trimming,telomere is the clock of a biological cell,if it's length is too short the cell cannot multiply,a human cell can divide maximum 50 times,if it increase more, our life span may increase considerably.
Certain proteins undergo oxidisation which are known to be associated with ageing and some age related diseases,when people turn about 80 approximately half of the bady proteins are damaged due to oxidation,the oxidation occurs because of random chemical degradation,that are associated with convention of food particles to enregy( metabolism) .
Protein's misfoldings are another reason for ageing,when native proteins are synthesised in our cells,which is in helical(Alfa helical)structure and…

HOW THE CORONA VIRUS INFECT HUMAN?

WHAT IS CORONA VIRUS?

Dear friends ,today the world is under a dangerous pandemic the COVID-19 so-many people dying word wide,so I think it is necessary to write on corona virus,how ever our regular subject remain 'human aging'
Before going the details of corona virus we should know what is viruses,
What is virus?In1886 Adolf mayor,a German agricultural chemist who first described about a disease,the tobacco mosaic disease,mosaic like appearance on leafs of tobacco plant.later Martinus Beijerich given the name Virus,Virus is a latin word,means a poisonous subsance                                        Viruses are generally considered as non living things, but they active when enter a host cell.they consist of genetical codes(the RNA or DNA)body is covered  by a protein coat,which is known as. Capsids,in some virus especially in the case of novel corona virus the capsid is covered by two layers of lipids,which is known as envelop.viruses cannot multiply themself,they must enter living cell. When they…

What is protein?

What is protein?
Protein is the basic components of living cells,it made of carbon,hydrogen,nitrogen and one or more chain of amino acids.Like carbohydrate and fats protein is a macro nutrient it is commonly available in animal products,eggs, meat, milk,yoghurt etc,it also available in beens, nuts,legumes etc.Proteins makeup 15 % of a person's body weight  According to their structure there are three types of proteins are there,they are fibrous, globular,and membrane.Fibrous proteins forms muscle fibre,bones,connetive tissues and tendons,eg;actin,myosin,karatin.Globular protein is water soluble,they have so many functions in our body such as transporting,catalysing,and regulating ,eg; albumin,alphaglobin,hemoglobin etc.  According to their functions proteins are catagarised to eight groups,they are hormones, defensive proteins, enzymatic proteins,transport proteins,structural proteins,storage proteins,receptor proteins and contractile proteins. Hormones: are protein based secretion o…

Why we are getting old?

Why we are getting old?

The answer is simple,the 'errors'.The errors that happening during cell multiplication and by the influences of external factors.So Many changes happens in DNA every year,most important one is the shortening of telomeres.A telomere is the tail end of chromasome.The free radical theory of -ageing, which devolved in1950 says that the reactive oxygen species(ROS)  produced during mitochondrial functions react with their DNA (mtDNA)  and other cell organelles, makes sever damage and declined mitochondrial functions that leads us to aging.ROS is produced when mitochondria make energy from food particles,when we eat more the mitochondria produce more energy and more ROS also evolved as by product.So having a comparatively limited amount of diet may be better to increase life span
In the year 1961 an American scientist L.Hayflick discovered that human cells have limited capacity to divide.Human cells are not able to divide again after 50 cell divisions,this cond…