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Human ageing

Lipids&ageing

Cellinsight Everything about human ageing and related diseases Lipids Lipids are organic compounds, basically hydro carbons . They are non-polar ( means they don't have negatively or positively charged ends ) so they are not soluble in Water, but easily soluble in organic solvents such as chloroform, acetone, benzene,alcohol etc. Fats , oil , wax etc, are the examples of lipids . Lipids are necessary to make cell membranes, the outer most two layers of cell membrane is made up of phospholipids , which protect cell from surroundings and also helps cell more strong and flexible. Energy storage ( excess energy stored in adipose tissue in our body and used when ever needed ), they used to transmit nerve impulses, and many more..  Lipid metabolism Image credit goes to Commons.wikimedia.org           ( under common creative atribution)  Endocrine system in our body, releasing hormones which control growth and metabolism. According to their chemical structure hormones  are cla
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Role of protein on ageing


Role of protein on ageing
Protein structure 

Role of protein on aging 

Protein which controls the length of telomere are telomerase and a protein complex known as shelterin.a new study by Scripps Reserch Institute (TSRI) discovered a new protein named as TZAP (telomeric zinc associated protein)which decrease the length of telomeres by trimming,telomere is the clock of a biological cell,if it's length is too short the cell cannot multiply,a human cell can divide maximum 50 times,if it increase more, our life span may increase considerably.
Certain proteins undergo oxidisation which are known to be associated with ageing and some age related diseases,when people turn about 80 approximately half of the bady proteins are damaged due to oxidation,the oxidation occurs because of random chemical degradation,that are associated with convertion of food particles to energy ( metabolism) .
Protein's mis foldings are another reason for ageing,when native proteins are synthesised in our cells,which is in helical(Alfa helical)structure and everything fine,but in some cases the proteins produced are mis folded and which are considered as minimum energy state proteins,these proteins are useless or even toxic.these proteins are insoluble in water,where as good proteins are soluble,these mis folded proteins later form a long lenear aggregate known as amyloid diposit,these deposit causes diseases also,for example Alzheimer's disease.
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